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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRAS
All Species:
12.12
Human Site:
S148
Identified Species:
20.51
UniProt:
P10301
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10301
NP_006261.1
218
23480
S148
G
N
K
A
D
L
E
S
Q
R
Q
V
P
R
S
Chimpanzee
Pan troglodytes
XP_524339
218
23448
S148
G
N
K
A
D
L
E
S
Q
R
Q
V
P
R
S
Rhesus Macaque
Macaca mulatta
XP_001115362
218
23436
A148
G
N
K
A
D
L
E
A
Q
R
Q
V
P
R
S
Dog
Lupus familis
XP_533617
218
23548
T148
G
N
K
A
D
L
E
T
Q
R
Q
V
P
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P10833
218
23745
N148
G
N
K
A
D
L
E
N
Q
R
Q
V
L
R
S
Rat
Rattus norvegicus
P97538
208
23869
T146
D
Q
G
K
E
M
A
T
K
Y
N
I
P
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519605
176
20687
R119
E
E
G
Q
Q
L
A
R
Q
L
K
V
T
Y
M
Chicken
Gallus gallus
P08642
189
21347
D132
V
E
T
R
Q
A
Q
D
L
A
R
S
Y
G
I
Frog
Xenopus laevis
Q7ZXH7
184
20815
G127
L
E
D
E
R
V
V
G
K
E
Q
G
Q
N
L
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
G127
L
E
D
E
R
V
V
G
K
E
Q
G
Q
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04388
192
22217
N135
V
S
L
E
E
A
Q
N
T
S
R
N
L
M
I
Honey Bee
Apis mellifera
XP_393035
199
23005
V138
D
Y
H
R
V
I
E
V
E
E
A
Q
N
R
A
Nematode Worm
Caenorhab. elegans
NP_496623
212
24407
N136
G
N
K
A
D
L
E
N
E
R
H
V
A
R
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P22126
213
24008
S151
G
T
K
Y
I
E
T
S
A
K
T
Q
H
N
V
Conservation
Percent
Protein Identity:
100
99.5
99
97.7
N.A.
94.5
49
N.A.
52.2
48.6
44.9
44.9
N.A.
56.8
56.8
55.5
N.A.
Protein Similarity:
100
99.5
99.5
99.5
N.A.
97.2
60
N.A.
61.9
60
58.2
58.2
N.A.
69.2
69.2
64.2
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
6.6
N.A.
20
0
6.6
6.6
N.A.
0
13.3
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
40
N.A.
26.6
13.3
20
20
N.A.
33.3
33.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
51.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
65.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
43
0
15
15
8
8
8
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
15
0
43
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
29
0
22
15
8
50
0
15
22
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
15
0
0
0
0
15
0
0
0
15
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
8
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
22
% I
% Lys:
0
0
50
8
0
0
0
0
22
8
8
0
0
0
0
% K
% Leu:
15
0
8
0
0
50
0
0
8
8
0
0
15
0
15
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
43
0
0
0
0
0
22
0
0
8
8
8
22
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
36
0
0
% P
% Gln:
0
8
0
8
15
0
15
0
43
0
50
15
15
0
0
% Q
% Arg:
0
0
0
15
15
0
0
8
0
43
15
0
0
50
0
% R
% Ser:
0
8
0
0
0
0
0
22
0
8
0
8
0
0
36
% S
% Thr:
0
8
8
0
0
0
8
15
8
0
8
0
8
0
0
% T
% Val:
15
0
0
0
8
15
15
8
0
0
0
50
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
0
0
8
0
0
8
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _